Chemotherapy of germinal tumors

Chemotherapy for brain tumors.

Traditionally, cytotoxic drugs have played a limited role in the treatment of brain tumors, but important advances in chemotherapy have occurred during the past decade. Certain central nervous system (CNS) malignancies are remarkably chemosensitive. These include primary CNS lymphoma, medulloblastoma, oligodendroglioma, and intracranial germ-cell tumors. This review focuses on advances in the c...

Chemotherapy for Brain Tumors

悪性腫瘍 に対す る化学療 法の原則 には3通 りの仮定が あ る.第1は 治癒 するためにはすべての腫瘍 細胞が死滅 し,除 去 され なければな らない とす る説,第2は 生体 に は免疫学 的防御機構 が存 在す るか ら,あ る数 まで腫瘍 細 胞 を減 らす ことができれ ば,あ とは生体 の 自然 に備わ っ た防衛能 力で治癒 す ることができる とす る説,そ して第 3は,悪 性腫瘍 細胞を分化す ることがで きれば,た とえ 腫瘍 細胞が存 在 していて も増殖,転 移 によって生体 に悪 影響 を及ぼす ことな く,正 常組織 と平和共存で きるであ ろ うとする仮説 である.残 念 なが ら今 目,こ の仮説のい ずれが正 しいのか,そ の詳細は不明であ る.現 実的 には 悪性腫瘍 細胞 を減 らすためには5種 類 の治療 方 式 が あ る.す なわち,...

The chemotherapy of intrathoracic tumors.

The role of radiotherapy and chemotherapy in management of thyroid tumors [Persian]

  Radioiodine (1-131) is the treatment of choice in differentiated thyroid carcinoma. External radiotlierapy however, has it's own roie in these tumors. Treatment of anaplastic thyroid carcinoma 1ms not acliieved any notahle success yet, though combined - modality regimens of radiotherapy and chemotherapy have sometimes shown significant results. In this paper the rol...

Main Determinants of Severe Neutropenia in Patients with Solid Tumors Receiving Adjuvant Chemotherapy

Background:Chemotherapy-induced neutropenia as a major toxicity of systemic chemotherapy is commonly associated with substantial mortality and morbidity, and thus identifying its determinants is necessary. This study was undertaken to identify main risk factors of severe neutropenia following adjuvant chemotherapy treatment in a community-based population of patients with cancer in Semnan, I...